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Vol. 1 (2025)
Open Access Review

Applications of Large Models in Medicine

by Yunhe Su 1 ,  Zhengyang Lu 3 ,  Junhui Liu 4 ,  Ke Pang 5 ,  Haoran Dai 6 ,  Sa Liu 2 ,  Yuxin Jia 7 ,  Lujia Ge 8  and  Jing-min Yang 9,*
1
The First Clinical Medical School, Mudanjiang Medical University, Mudanjiang 157011, China
2
Department of Computer Science, University of California - Davis, California 95616, USA
3
School of Design, Jiangnan University, Wuxi 214122, China
4
First Moscow State Medical University, Moscow 119991, Russian Federation
5
Department of Anesthesiology, Third Xiangya Hospital, Central South University, Changsha 410013, China
6
Nanjing Medical University, Nanjing 211166, China
7
Brown School, Washington University in St.Louis, Missouri 63130, USA
8
School of Basic Medical Sciences, Capital Medical University, Beijing 528415, China
9
WestChina Biomedical Big Data Center, WestChina Hospital, Sichuan University, Chengdu 610000, China
*
Author to whom correspondence should be addressed.
AI Med  2025 1(1):4; https://doi.org/10.71423/aimed.20250105
Received: 3 January 2025 / Accepted: 2 February 2025 / Published Online: 12 February 2025
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Abstract

This paper explores the advancements and applications of large‐scale models in the medical field, with a particular focus on Medical Large Models (MedLMs). These models, encompassing Large Language Models (LLMs), Vision Models, 3D Large Models, and Multimodal Models, are revolutionizing healthcare by enhancing disease prediction, diagnostic assistance, personalized treatment planning, and drug discovery. The integration of graph neural networks in medical knowledge graphs and drug discovery highlights the potential of Large Graph Models (LGMs) in understanding complex biomedical relationships. The study also emphasizes the transformative role of Vision‐Language Models (VLMs) and 3D Large Models in medical image analysis, anatomical modeling, and prosthetic design. Despite the challenges, these technologies are setting new benchmarks in medical innovation, improving diagnostic accuracy, and paving the way for personalized healthcare solutions. This paper aims to provide a comprehensive overview of the current state and future directions of large models in medicine, underscoring their significance in advancing global health.

Keywords: Medical Models; Large Language Models; Vision Models; Multimodal Models; Drug Discovery;
Copyright: © 2025 by Su, Lu, Liu, Pang, Dai, Liu, Jia, Ge and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (Creative Commons Attribution 4.0 International License). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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APA Style
Su, Y., Lu, Z., Liu, J., Pang, K., Dai, H., Liu, S., Jia, Y., Ge, L., & Yang, J. (2025). Applications of Large Models in Medicine. AI Med, 1(1), 4. doi:10.71423/aimed.20250105
ACS Style
Su, Y.; Lu, Z.; Liu, J.; Pang, K.; Dai, H.; Liu, S.; Jia, Y.; Ge, L.; Yang, J. Applications of Large Models in Medicine. AI Med, 2025, 1, 4. doi:10.71423/aimed.20250105
AMA Style
Su Y., Lu Z., Liu J. et al.. Applications of Large Models in Medicine. AI Med; 2025, 1(1):4. doi:10.71423/aimed.20250105
Chicago/Turabian Style
Su, Yunhe; Lu, Zhengyang; Liu, Junhui; Pang, Ke; Dai, Haoran; Liu, Sa; Jia, Yuxin, and et al. 2025. "Applications of Large Models in Medicine" AI Med 1, no.1:4. doi:10.71423/aimed.20250105

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APA Style
Su, Y., Lu, Z., Liu, J., Pang, K., Dai, H., Liu, S., Jia, Y., Ge, L., & Yang, J. (2025). Applications of Large Models in Medicine. AI Med, 1(1), 4. doi:10.71423/aimed.20250105
ACS Style
Su, Y.; Lu, Z.; Liu, J.; Pang, K.; Dai, H.; Liu, S.; Jia, Y.; Ge, L.; Yang, J. Applications of Large Models in Medicine. AI Med, 2025, 1, 4. doi:10.71423/aimed.20250105
AMA Style
Su Y., Lu Z., Liu J. et al.. Applications of Large Models in Medicine. AI Med; 2025, 1(1):4. doi:10.71423/aimed.20250105
Chicago/Turabian Style
Su, Yunhe; Lu, Zhengyang; Liu, Junhui; Pang, Ke; Dai, Haoran; Liu, Sa; Jia, Yuxin, and et al. 2025. "Applications of Large Models in Medicine" AI Med 1, no.1:4. doi:10.71423/aimed.20250105

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